孖寶來到安憩老人院，發現整間老人院只餘下五名老人家住著，由神化的院長(林敏驄 飾)，愛心爆棚看護清清（王菀之 飾）照顧，起初孖寶以為這五位老人家看上去全都癡癡呆呆，毫無威脅，但其實個個古靈精怪，更身懷絕技；神偷強叔(泰迪羅賓飾)， 曾經是粵劇名伶演技超凡的惠珍(恬妞 飾)，腦退化幹探肥蟹（洪金寶 飾），孔武有力的龍哥(梁小龍 飾)，飽經江湖歷煉的梁伯(吳耀漢 飾)，孖寶破壞老人院的計劃，早就比老人家們發現，反被老人家們整蠱。
In the long tradition of the celebrating Chinese New Year movies, we are proud to introduce A Lifetime Treasure.
In a peaceful elderly home, life goes on around these unique persons: Master (starring Andrew Lam) the caring retired doctor who spent his life travelling the world to help people and now manages this elderly home. He has help from Ching (starring Ivana Wong), a nurse who work for him in all his previous adventures. Together, they take care of a group or lovely 5 retirees.
Teddy (starring Teddy Robin) an ex-professional pickpocket, Fatty Crab (starring Sammo Hung) a very smart ex-detective but now in a wheel chair, Uncle Lung (starring Leung Siu Lung) an ex-spy for the British secret service who vow to keep his mouth shut after the retirement, the sad Richard (starring Richard Ng) an ex-professional swimmer whose son died in sea few years back and finally the elegant Wai (starring Tien Niu) a retired Chinese opera actress.
The well balance life of the elderly home is about to be shaken, when the gangster Marvin (starring Lam Suet) an old friend of Master, trying to set up a trap to take revenge on him…